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Abstract #1822

Estimation of GABA and Glutamergic Contents in Occipital Lobe and Cerebellum By1H MR Spectroscopy

Saadallah Ramadan1, Tapan Biswas2, Keith Heberlein3, Mark Brown4, Alexander Lin5

1School of Health Sciences, University of Newcastle, Callaghan, New South Wales, Australia; 2Biswas X Ray & Scan Center,, West Apcar gardens, Asansol, India; 3Siemens Medical Solutions, Charlestown, MA, United States; 4Training and Development Center, Siemens Healthcare, Cary, NC, United States; 55Center for Clinical Spectroscopy, Brigham and Women's Hospital, Boston, MA, United States

Glx and GABA were measured in cerebellum and occipital lobe of human brain (n=24). Ratio of Glx peaks at 3.8 and 2.3 ppm, as well as GABA peak at 3.0ppm to NAA was calculated. Higher levels of GABA and Glx were found in cerebellum. This is in accordance with known function of cerebellum in