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Abstract #1833

Diffusion Properties of Metabolites in the Corpus Callosum at 7T: White Matter Microstructure and Metabolite Compartmentation

Itamar Ronen1, Robert Rengelink2, Ece Ercan1, Andrew Webb1

1C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands; 2Department of Physics, Leiden University, Leiden, Netherlands

In this work we investigated the diffusion properties of brain metabolites in a well-organized white matter fiber bundle, i.e. the corpus callosum, at 7T. The results indicate a clear difference in compartmentation among metabolites and raise interesting questions when results are fitted to conventional models of diffusion in given geometries.