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Abstract #1957

How the Spatial Distribution of the Vessels Affects T2*? a 2D Simulation Study.

Nicolas Pannetier1, 2, Clement Debacker, 13, Franck Mauconduit, 13, Christen Thomas4, Emmanuel Barbier, 13

1Grenoble Institut des Neurosciences, Universite Joseph Fourier, Grenoble, France; 2Department of Radiology & Biomedical Imaging, University of California, San Francisco, CA, United States; 3U836, INSERM, Grenoble, France; 4Department of Radiology, Stanford University, Stanford, CA, United States

We investigated how the spatial distribution of the vessels impacts the relaxation rate T2* of the MR signal. We used simulation in 2D with different constraints on the vessels distribution. We found that at 7T, the distribution of the vessels may impacts for about 8% the SO2 estimates. Moreover we found an interesting linear relationship between T2* and a spatial frequency that characterizes the distribution of the vessels.