Abstract #1976

DCE-MRI Using a Three Compartment Leaky Tracer Kinetic Model (LTKM) for Whole Body Applications

Ram KS Rathore¹, Rakesh Kumar Gupta², Prativa Sahoo¹, Rishi Awasthi², Divya Rathore¹, Bhaswati Roy²

¹Mathematics & Statistics, Indian Institute of Technology, Kanpur, Kanpur, Uttar Pradesh, India; ²Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India

A three compartment tissue model - Leaky Tracer Kinetic Model (LTKM) is introduced to take care of the varied tissue natures in the whole body applications of DCE-MRI. In particular it takes care of vasculature in accessible leakage and provides a consistent determination of the perfusion parameters. Applications of it elsewhere have led to a better grading of tumors.