Look-Locker Acquisition for Estimation of Partial Volume Fractions in ASL Data

Jan Petr¹, Georg Schramm¹, Frank Hofheinz¹, Jens Langner¹, Jrg Steinbach¹, Jrg van den Hoff¹

Partial volume correction becomes an important issue in arterial spin labeling. It is usually done using the partial volume maps obtain by segmenting the high resolution T₁-weighted images. This brings additional issues with imperfections in segmentation and corrections of image distortion. We propose an alternative by using T₁ relaxation times obtained from the Look-Locker sequence to directly obtain the partial volume ratios. These ratios show higher agreement with the perfusion data than the standard T₁-weighted images segmentation.