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Abstract #2067

Optimization of Diffusion-Weighted FMRI at 3T MRI Compare with BOLD-FMRI

Li-Ming Hsu1, Kuan-Hung Cho2, Cyril Poupon3, Denis Le Bihan3, Ching-Po Lin, 14

1Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 2Instrumentation Resource Center, National Yang-Ming University, Taipei, Taiwan; 3NeuroSpin, IFR 49 CEA Saclay, Gif-sur-Yvette, France; 4Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

To optimize the diffusion-fMRI at different b-values by considering the signal performance compared with BOLD-fMRI during visual stimulation. The results show that the DfMRI at b-value = 1,200 s/mm2 should be a better choice than b-value = 600 and 1,800 s/mm2. DfMRI could provides the chance to approach the neuron activation than hemodynamic response.