Abstract #2067

Optimization of Diffusion-Weighted FMRI at 3T MRI Compare with BOLD-FMRI

Li-Ming Hsu¹, Kuan-Hung Cho², Cyril Poupon³, Denis Le Bihan³, Ching-Po Lin,¹⁴

¹Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; ²Instrumentation Resource Center, National Yang-Ming University, Taipei, Taiwan; ³NeuroSpin, IFR 49 CEA Saclay, Gif-sur-Yvette, France; ⁴Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

To optimize the diffusion-fMRI at different b-values by considering the signal performance compared with BOLD-fMRI during visual stimulation. The results show that the DfMRI at b-value = 1,200 s/mm² should be a better choice than b-value = 600 and 1,800 s/mm². DfMRI could provides the chance to approach the neuron activation than hemodynamic response.