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Abstract #2120

The foot-Print of Memory Encoding on the Brain

Deng Mao1, Kuang-Chi Tung1, Peiying Liu1, Yong He2, Jinhui Wang2, Hanzhang Lu1

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China

A number of evidences have suggested that the resting brain can be modulated by recent experience. However, few reports have demonstrated the feasibility to measure brain changes after merely minutes of use. Here, we used a 20-min memory encoding task to stimulate the brain, and collected fcMRI data (under resting state) before and after the task. We compared resting brain networks between these two time points and demonstrated that fcMRI brain networks can be modified in the acute phase using a memory task. Finally, we correlated the extent of connectivity change with the behavioral data of memory scores across individuals.