Brain Performance Correlations with Oxygenation Levels and Neuronal Activity in Resting State FMRI

David Matthew Carpenter¹, Edmund Wong¹, Jessica Roman¹, Cheuk Ying Tang¹, ²

Here we used the random fluctuations of the resting state brain and capitalized on the hemodynamic delay of BOLD fMRI to investigate what primes the brain for best performance: preceding blood oxygenation levels or preceding neuronal activity. The results show correlation between response time (at T=0) and blood oxygen levels of the default network (BOLD at T=0) but not with neuronal activity of the network (BOLD at T=2sec). Subjects performance was correlated to the oxygen level and not the neuronal activity immediately preceding level of activity.