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Abstract #2168

Longitudinal FMRI of Spontaneous Plasticity in Rats After Focal Stroke Under Alpha-Chloralose Anesthetic

Tobias C. Wood1, Denise Duricki2, Lawrence Moon2, Camilla Simmons1, Michel Mesquita1, Steven Williams1, Diana Cash1

1Department of Neuroimaging, King's College London, London, United Kingdom; 2Wolfson Centre for Age Related Diseases, King's College London

We present a longitudinal fMRI study of focal stroke recovery in adult rats under Alpha-Chloralose anesthetic using forepaw stimulation. Spontaneous plasticity was observed, confirming this protocol is suitable for use with repeated imaging experiments.