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Abstract #2358

Studying the Effects of Homodyne High Pass Filtering on Susceptibility Mapping Using a Simulated 3D Brain Model

Sagar Buch1, E. Mark Haacke2, 3, Saifeng Liu1, Jaladhar Neelavalli2

1School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada; 2The Magnetic Resonance Imaging Institute for Biomedical Research, Detroit, MI, United States; 3Academic Radiology, Wayne State University, Detroit, MI, United States

Homodyne high pass filter and SHARP method, which are commonly used to remove the background field variations from the real phase data, are used to process the phase images produced from a simulated 3D model of the brain, which includes the geometries of basal ganglia and grey matter/white matter. Susceptibility maps (SMs) of the processed simulations are compared with that of the real phase images. A negative susceptibility region, seen in both simulated and real phase data, is discussed as a possible artifact caused by the processing techniques after comparing the simulated SMs produced from unprocessed and processed phase data.