Improved Quantitative Susceptibility Mapping (QSM) with HEIDI

Ferdinand Schweser¹, Karsten Sommer¹, Andreas Deistung¹, Jrgen Rainer Reichenbach¹

Quantitative susceptibility mapping (QSM) is a novel imaging technique that determines tissue magnetic susceptibility from the phase of complex gradient-echo data. Due to the ill-posed nature of this inverse problem, regularization strategies are required to reduce streaking artifacts on the computed susceptibility maps. This paper presents an improved QSM algorithm, Homogeneity Enabled Incremental Dipole Inversion (HEIDI), which utilizes a sophisticated problem-specific incremental inversion procedure and a priori information on the homogeneity of the susceptibility distribution.