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Abstract #2359

Improved Quantitative Susceptibility Mapping (QSM) with HEIDI

MAGNA25Ferdinand Schweser1, Karsten Sommer1, Andreas Deistung1, Jrgen Rainer Reichenbach1

1 Medical Physics Group, Dept. of Diagnostic and Interventional Radiology I, Jena University Hospital, Jena, Germany

Quantitative susceptibility mapping (QSM) is a novel imaging technique that determines tissue magnetic susceptibility from the phase of complex gradient-echo data. Due to the ill-posed nature of this inverse problem, regularization strategies are required to reduce streaking artifacts on the computed susceptibility maps. This paper presents an improved QSM algorithm, Homogeneity Enabled Incremental Dipole Inversion (HEIDI), which utilizes a sophisticated problem-specific incremental inversion procedure and a priori information on the homogeneity of the susceptibility distribution.