Improved Diffusion-Weighted Body Imaging Using High-Order Eddy Current Correction and Smart Combination

ZHIQIANG LI¹, Dan Xu², Kenichi Kanda¹

Single-shot DW-EPI of the liver has the drawback in signal loss due to cardiac motion. Smart combination has been proposed to mitigate this issue, but requires double spin-echo diffusion to avoid mis-registration between the individual source images acquired with single spin echo (SSE) diffusion, with the trade-off in SNR. High-order eddy-current (HOEC) correction has been presented to minimize the mis-registration in data acquired with SSE. In this work, we apply both HOEC correction and smart combination on SSE DW-EPI to demonstrate the feasibility of generating liver image with high SNR, minimal signal loss and mis-registration.