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Abstract #2446

Improved Diffusion-Weighted Body Imaging Using High-Order Eddy Current Correction and Smart Combination

ZHIQIANG LI1, Dan Xu2, Kenichi Kanda1

1MR Engineering, GE Healthcare, Waukesha, WI, United States; 2Applied Science Laboratory, GE Healthcare, Waukesha, WI, United States

Single-shot DW-EPI of the liver has the drawback in signal loss due to cardiac motion. Smart combination has been proposed to mitigate this issue, but requires double spin-echo diffusion to avoid mis-registration between the individual source images acquired with single spin echo (SSE) diffusion, with the trade-off in SNR. High-order eddy-current (HOEC) correction has been presented to minimize the mis-registration in data acquired with SSE. In this work, we apply both HOEC correction and smart combination on SSE DW-EPI to demonstrate the feasibility of generating liver image with high SNR, minimal signal loss and mis-registration.