Abstract #2572

Quantitative Comparison of the Informational Content of T2*-Weighted Magnitude, Phase and SWI 7T MR Data by Means of Texture Analysis of the Cortical Ribbon in Elderly Subjects

N. T. Doan¹, S. van Rooden², M. J. Versluis², A. G. Webb², J. van der Grond, M. A. van Buchem, J. H. C. Reiber¹, J. Milles¹

¹LKEB - Department of Radiology, Leiden University Medical Center, Leiden, Zuid Holland, Netherlands; ²CJ Gorter Center - Department of Radiology, Leiden University Medical Center, Leiden, Zuid Holland, Netherlands

The aim of this work is to investigate and compare the information content of T2*-weighted magnitude, phase and SWI data by means of texture analysis. Textural features of the cerebral cortex on magnitude, phase or SWI images were derived based on Gray Level Co-occurrence Matrix. Subsequently, classification using respectively magnitude-based, phase-based and SWI-based features was carried out with a Fisher linear discriminant classifier and a leave-one-out cross-validation approach. The results suggest that, from a texture information perspective, phase images have higher information content than either magnitude or SWI images.