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Abstract #2978

Evaluation of the Kinetic Properties of Background Parenchymal Enhancement Across Phases of the Menstrual Cycle

Jason McKellop1, Alana Amarosa1, Tess Clendenen2, Melanie Moccaldi1, Anne Zeleniuch-Jacquotte2, Linda Moy1, Sungheon Kim1

1Radiology, NYU School of Medicine, New York, NY, United States; 2Environmental Medicine, NYU School of Medicine, New York, NY, United States

It has been shown that background parenchymal enhancement (BPE) is strongly associated with the menstrual cycle as well as breast cancer. However, it has not been shown whether the kinetics of dynamic contrast enhancement is also associated with the menstrual cycle. In this study, BPE was measured in premenopausal patients with benign breast lesions and compared across menstrual phases. Statistically significant differences were found between the 4th week and early phases of menstruation in terms of early enhancement slope (p=.02) and delayed enhancement (p=.01).