Meeting Banner
Abstract #3005

Simulations of the Impact of TWIST View Sharing on the Measured Enhancement in Breast DCE MRI

Yuan Le1, Christian Geppert2, Randall Kroeker2, Brian Dale2, Chen Lin1

1Radiology, Indiana University, Indianapolis, IN, United States; 2Siemens Healthcare, Erlangen, Germany

Computer simulations have been performed to study the error caused by TWIST view sharing on the measured breast dynamic contrast enhancement. A digital breast phantom was generated with spherical lesions of different sizes and three types of enhancement curves: persistent, plateau and wash-out. The results suggest that for lesion larger than 5mm, TWIST view sharing with greater 33% central k-space region and more than 50% peripheral sampling density would preserve the curve type information. Such imaging parameters are suitable for clinical breast DCE MRI.