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Abstract #3141

Inferior Frontal Gray Matter Is Increased in Healthy Individuals with High Risk Averse Behaviour.

Satomi Higuchi1, Keigo Inukai2, Hackjin Kim3, Tetsuya Matsuda4, Masamichi Sakagami, Tatsuya Kameda

1Center for Experimental Research in Social Science, Hokkaido University, Sapporo, Hokkaido, Japan; 2Graduate School of Economics and Business Administration, Hokkaido University, Japan; 3Department of Brain and Cognitive Engineering, Korea University; 4Tamagawa University, Japan

A gambling task used for risk measurement, known as mean variance utility mode (MVUM), was used to estimate individuals risk attitude. In clinical studies, the `Iowa gambling task` is a test for measuring risk attitude in relation to addiction. However, this model differs in that outcome feedback is also measured, and therefore not purely representative of decision making. In this work we measured individual responses to MVUM, obtained T1 weighted MRI and applied VBM analysis, investigating gray matter volumes (GMV) of healthy volunteers and their behavioural risk attitude. GMV and risk aversion were positively correlated in left inferior frontal gyrus.