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Abstract #3183

Preoperative Assessment of Meningioma Stiffness by MR Elastography

Matthew C. Murphy1, John Huston, III1, Kevin J. Glaser1, Armando Manduca2, Fredric B. Meyer3, Giuseppe Lanzino3, Joel P. Felmlee1, Richard L. Ehman1

1Department of Radiology, Mayo Clinic, Rochester, MN, United States; 2Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, United States; 3Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States

Meningiomas vary in stiffness and the ease of resection is in part determined by the consistency of the tumor. A noninvasive method for measuring tumor stiffness would improve preoperative planning and more accurately assess the risk of surgery. However, current imaging methods have limited ability to predict the mechanical properties of meningiomas. The purpose of this work was to perform a pilot study to determine if MR elastography shows merit for measuring meningioma stiffness noninvasively.