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Abstract #3221

The Clinical Application of 3T PROPELLER DUO MRI Quantitative Analysis of Extraocular Muscle in Gravesophthalmopathy

Ketao Mu1, Jing Zhang1, He Wang2, Jianpin Qi1, Wenzhen Zhu1

1Radiology, Tongji Hospital,Tongji Medical CollegeHuazhong University of Science & Technology, Wuhan, Hubei, China; 2Applied Science Lab, GE Healthcare, Shanghai, China

Our objective was to prospectively investigate extraocular muscle in patients with GO utilizing 3T PROPELLER DUO MRI and determine whether apparent diffusion coefficients(ADC)parameters correlate with disease severity.We finally come to the conclution that PROPELLER DUO MRI has been shown to helpful to diagnose intraorbit disease, measuring ADC values can further increase confidence of its detection. A significant positive correlation between maxADC and disease severity was observed.We can judge patients whether in active phase or not by measuring the ADC values of extraocular muscle, to guide clinical treatment and predict the responsiveness to immunosuppressive therapy.