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Abstract #3232

Cortical Thicknesses Determination from High Resolution MPRAGE and MP2RAGE Data at 7 T

Shan Yang1, Astrid Wollrab1, Falk Lsebrink1, Meng Li2, Martin Walter2, Oliver Speck1

1Biomedical Magnetic Resonance, Otto-von-Guericke-University, Magdeburg, Sachsen-Anhalt, Germany; 2Clinical Affective Neuroimaging Laboratory, Department of Psychiatry, Otto-von-Guericke-University, Magdeburg, Sachsen-Anhalt, Germany

Computer-based brain morphometry is widely used in neurological and psychiatric diseases studies, such as depression, Alzheimers disease and autism. 7 T MRI allows for higher resolution, but suffers strongly from B1 inhomogeneities. Recently, two methods, MPRAGE image division by GE image and MP2RAGE, have been proposed to remove such inhomogeneities. In this work, we calculate the cortical thickness estimation from high resolution MPRAGE and MP2RAGE MRI and compare different tissue segmentation tools.