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Abstract #3240

High Resolution In-Vivo Brain Frequency Shift and Susceptibility Imaging at 3T

Wei Li1, Bing Wu1, Chunlei Liu1, 2

1Brain Imaging & Analysis Center, Duke University, Durham, NC, United States; 2Radiology, Duke University, Durham, NC, United States

Frequency shift and susceptibility images from gradient echo MRI have unique advantages of high contrast and signal-noise-ratio. They two complement each other and provide a promising combination for high resolution brain imaging. In this study, we demonstrated the high resolution frequency shift and susceptibility imaging with excellent SNR at 3T, using optimized image acquisition and post processing methods. The resulting frequency shift and susceptibility images show excellent delineation of deep brain nuclei, the hippocampus and cerebellar nuclei with excellent anatomical details.