Abstract #3280

Determination of Oxygen Consumption in Calf Muscle Through Combined ASL Perfusion and T2 Oxymetry Measurements at 3.0 T.

Nicolas Decorte¹, Ericky Caldas de Almeida Araujo², Alexandre Vignaud³, Pierre G. Carlier²

¹Institute of Myology, AIM and CEA , Paris, 75013, France; ²Institute of Myology, AIM and CEA, Paris, 75013, France; ³Siemens Healthcare, Saint Denis, France

Functional NMR imaging, among its many variations, offers the possibility to measure non-invasively muscle perfusion by arterial spin labeling (ASL) and blood oxygenation via the T2 dependence on haemoglobin saturation. In this study, we show that muscle ASL and T2 determination of arterial and venous blood may be combined to calculate muscle oxygen consumption non-invasively and with a temporal resolution compatible with physiological studies.