Improving Accuracy of Susceptibility and Oxygen Saturation Quantification of Veins Using Correcting Factor Method

Jin Tang¹, Saifeng Liu¹, Jaladhar Neelavalli², Yu-Chung Norman Cheng², E Mark Haacke¹, ²

Mapping susceptibility from field perturbation data often uses a high pass filter to remove the low spatial frequency phase, however, using high pass filter will result in a concomitant loss of important local phase information and lead to decreases of susceptibility values inside vessels, especially for large vessels. To solve this problem and to improve the accuracy of susceptibility quantification of veins, we propose a new method which uses correcting factor (CF) to automatically adjust the underestimated susceptibility value inside the vein. The underestimated susceptibility values will be completely compensated by the CF.