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Abstract #3563

In Vivo Human Brain Measurements of Axon Diameter Distributions in the Corpus Callosum Using 300 MT/m Maximum Gradient Strengths

Jennifer A. McNab1, Thomas Witzel1, Himanshu Bhat2, Keith Heberlein2, Boris Keil1, Julien Cohen-Adad1, M. Dylan Tisdall1, Lawrence L. Wald1, 3

1A.A. Martinos Center for Biomedical Imaging, Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; 2Erlangen USA Inc., Siemens Medical Solutions, Charlestown, MA, United States; 3Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

In this work we use a novel gradient coil AS302 which is part of a new 3T system (MAGNETOM Skyra CONNECTOM, Siemens Healthcare) capable of up to 300 mT/m to measure, in the in vivo human brain, the full axon diameter distribution in the corpus callosum as determined by the AxCaliber method.