Abstract #3614

Visualizing Tractography Metrics of Cortical-Connectivity Integrity in Diffusion Imaging

Radu Jianu¹, Wenjin Zhou¹, Ryan Cabeen¹, Daniel Dickstein²,³, David H. Laidlaw¹

¹Computer Science, Brown University, Providence, RI, United States; ²Psychiatry & Human Behavior, Brown University, Providence, RI, United States; ³Bradley Hospital, Providence, RI, United States

We present a circular visualization interface of the tractography metrics for assessing cortical-connectivity integrity. We subdivided the gray matter into 80 regions-of-interest (ROIs) and calculated two metrics for each region-pair from the whole-brain tractography model produced from high angular resolution diffusion imaging. Three healthy control (HC) and three bipolar patients (BP) were examined in the visualization for their difference and location-specific changes in tractography metrics were identified.