Inter Hemispheric Transfer Time and Axon Diameter Properties of the Corpus Callosum

Assaf Horowitz¹, Daniel Barazany, Galit Yovel, Yaniv Assaf

The corpus callosum (CC) is one of the largest fiber systems in the brain connecting and transferring information between the two hemispheres. Axcaliber is a diffusion MRI methodology the thorough analysis of multi-diffusion time, high b value DWI acquisition, allows the estimation of the axon diameter distribution (ADD). In this study we aimed to examine the inter-hemispheric transfer time (IHTT) and its relation to different axonal properties of the CC. We found that the ADD micro-structural differences at different parts of the CC are the base for the behavioral reaction time (IHTT) differences.