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Abstract #3626

Multi-TE Diffusion Kurtosis Imaging in vivo

Alexandru Avram1, Arnaud Guidon2, Chunlei Liu3, Allen W. Song3

1Section on Tissue Biophysics and Biomimetics, NICHD, National Institutes of Health, Bethesda, MD, United States; 2Biomedical Engineering Department, Duke University, Durham, NC, United States; 3Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States

In this report we compare in vivo diffusion kurtosis measurements acquired with short and long echo times (TE) and discuss their potential for deriving a diffusional kurtosis measures for myelin water in vivo. Our findings provide initial evidence that the apparent kurtosis coefficient vary significantly with TE indicating differences between diffusional characteristics of T2 water pools in white matter.