Meeting Banner
Abstract #3773

Validation of a Faster Modified Look-Locker Inversion-Recovery (MOLLI) Method for Myocardial T1 Mapping on 3T MRI

Yoshiaki Morita1, Naoaki Yamada1, Teruo Noguchi2, Hiromi Hashimura1, Suzu Kanzaki1, Masahiro Higashi1, Hiroaki Naito1, Katsutoshi Murata3, Andreas Greiser4

1Department of Radiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; 2Division of Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan; 3Siemens Japan K.K., Tokyo, Japan; 4Siemens AG, Erlangen, Germany

Modified Look-Locker Inversion-recovery (MOLLI) sequence provides high resolution T1 map of myocardium. However, long breath holds often limit clinical application in patients due to motion artifact and heart rate variability. In this study, we proposed a faster MOLLI method that decreased by about one-third the acquisition time compared with the original-MOLLI, on 3T clinical machine. The proposed fast-MOLLI sequence is a rapid and reliable method for T1 estimation, with results very close to the original-MOLLI (mean T1 : fast-MOLLI 1140}43msec , original-MOLLI 1142}50msec). The fast-MOLLI will be of great help to understand the myocardial tissue characterization in various heart diseases.