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Abstract #3874

Clinical Validation of Non-Contrast Abdominal MRA with Quadruple Inversion-Recovery Prepared 3D B-SSFP

Iliyana Atanasova1, 2, Ruth Lim2, Hersh Chandarana2, David Stoffel2, Mary Bruno2, Daniel Kim3, Vivian Lee3

1Columbia University, New York, United States; 2New York University, New York, NY, United States; 3The University of Utah, Salt Lake City, UT

An inflow-based non-contrast angiography sequence with quadruple inversion-recovery preconditioning and 3D b-SSFP readout (NC-MRA) has been developed for abdominopelvic MRA. We evaluate the diagnostic accuracy of this method for detection of aortoiliac disease in 21 patients using gadolinium-enhanced MRA (CE-MRA) as a reference standard. Two blinded radiologists rated image quality, disease severity, and artifacts on a per-segment basis. Image quality of CE-MRA was superior to NC-MRA; however, 97% of all evaluated non-contrast segments were judged diagnostic. Of all evaluable segments with CE-MRA available, overall accuracy/sensitivity/specificity of NC-MRA was 93%/75%/95% respectively, indicating good diagnostic accuracy of the non-contrast technique.