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Abstract #3877

Vessel-Selective Non-Contrast Enhanced Time-Resolved MR Angiography Using PULSER Prepared 4D T1TFE in Intracranial Arteries

Masanobu Nakamura1, Masami Yoneyama1, Tomoyuki Okuaki1, Takashi Tabuchi1, Atsushi Takemura2, Makoto Obara2, Thomas Kwee3, Taro Takahara4, Satoshi Tsutsumi5

1Yaesu clinic, Tokyo, Japan; 2Philips Electronics Japan, Tokyo, Japan; 3University Medical Center Utrecht, Utrecht, Netherlands; 4Tokai University School of Engineering, Kanagawa, Japan; 5Juntendo University Urayasu Hospital, Chiba, Japan

We have proposed vessel - selective 3D volumetric non -contrast time- resolved MRA technique termed Contrast inherent inflow enhanced multi phase angiography ( v-sel CINEMA ). In this study the vessel selective PULSER preparation module was combined with a 4D T1 TFE readout that has previously been shown to generate time resolved MRA in healthy volunteers as well as in patients carrying cerebrovascular abnormalities. vsCINEMA could extract the blood flow in the whole brain at an interval of about 200 ms with a high degree of vessel specificity and showed good agreement compared to TOF-MRA and MR-DSA . vsCINEMA allows visualizing the dynamics of cerebral blood flow with high spatial and temporal resolutions. Patients carrying cerebrovascular pathologies such as AVM and moyamoya disease are good candidates for further investigations.