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Abstract #3879

Dynamic Non-Contrast Enhanced Angiography Based on Superselective Arterial Spin Labeling and Compressed Sensing

Michael Helle1, Mariya Doneva1, Matthias JP van Osch2, Peter Brnert1

1Research Laboratories, Philips Technologie GmbH, Innovative Technologies, Hamburg, Germany; 2C.J. Gorter Center for high field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

In the diagnosis of many cerebrovascular diseases highly resolved spatial and temporal images as well as vessel-selective information are required. Existing MR angiography techniques lack at least one of these demanded properties so that digital subtraction angiography (DSA) is still considered the gold-standard for cerebral angiography although the procedure is invasive and bears the risk of severe complications. In this study, superselective arterial spin labeling in combination with compressed sensing is employed to provide vessel-selective, temporally and spatially highly resolved angiograms with the potential to overcome limitations of existing MR methods and potentially provide the same information as with DSA.