Ferumoxytol Enhanced 2D & 3D Phase Contrast MRI in Dialysis Fistulas

Monica Sigovan¹, Gabriel Acevedo-Bolton¹, Petter Dyverfeldt¹, Christopher Owens², David Saloner¹

Ferumoxytol is a very promising MRI contrast agent for medical applications in which Gadolinium agents are contra-indicated. The quality of Phase Contrast MR acquisitions can be improved with the use of Gd. In comparison, Ferumoxytols higher r2* relaxivity could potentially induce strong intravoxel dephasing leading to errors in flow measurements. The objective was to evaluate ferumoxytols effect on 2D and 3D PC-MR flow imaging by simulations, In Vitro and in vivo imaging.