Monica Sigovan1, Gabriel Acevedo-Bolton1, Petter Dyverfeldt1, Christopher Owens2, David Saloner1
1Radiology, UCSF, San Francisco, CA, United States; 2Vascular Surgery, UCSF, San Francisco, CA, United States
Ferumoxytol is a very promising MRI contrast agent for medical applications in which Gadolinium agents are contra-indicated. The quality of Phase Contrast MR acquisitions can be improved with the use of Gd. In comparison, Ferumoxytols higher r2* relaxivity could potentially induce strong intravoxel dephasing leading to errors in flow measurements. The objective was to evaluate ferumoxytols effect on 2D and 3D PC-MR flow imaging by simulations, In Vitro and in vivo imaging.