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Abstract #3973

Gadolinium Contrast Enhanced Ultra-Short TE Imaging of Lung in Mice

Liya Wang1, 2, Xiaodong Zhong3, Xianghong Peng4, Jing Huang1, 2, Xiaofeng Yang5, Hui Mao1, 2

1Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States; 2Center for Systems Imaging, Emory University School of Medicine, Atlanta, GA, United States; 3MR R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States; 4Emory Winship Cancer Institute, Emory University, Atlanta, GA, United States; 5Radiation Oncology, Emory University School of Medicine, Atlanta, GA, United States


This study investigated the feasibility of gadolinium contrast agent enhanced UTE MRI of lung in mice on a standard 3 Tesla clinical MRI system with the goal to improve the image quality of pulmonary MRI. The results demonstrated that the administering gadolinium contrast agent combining with UTE acquisitions provide the high sensitivity and image contrast in MRI of lung. The gadolinium contrast enhanced UTE MRI of lung is dose-dependent and can be optimized.