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Abstract #3983

Regional Measurement of Respiratory Gas Arrival Time with Hyperpolarized Gas MRI

Kiarash Emami1, Yi Xin1, Puttisarn Mongkolwisetwara1, Harrilla Profka1, Jennia Rajaei1, Stephen J. Kadlecek1, Masaru Ishii2, Rahim R. Rizi1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Otolaryngology - Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, United States

Introduction of controlled pre-acquisition time delay in the existing fractional ventilation imaging technique provides a tool for determining regional gas arrival time constant, with a fairly similar implication to lung RC time constants on a regional basis. Results can alternatively be utilized to select a proper pre-acquisition time delay to minimize motion-induced errors and well mixing of inspired and residual gases in standard specific ventilation imaging applications with HP gas MRI.