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Abstract #4000

Dynamic Radial Imaging of Inhaled 129Xe and 3He

Helen Marshall1, Xiaojun Xu1, Graham Norquay1, Steve R. Parnell1, Juan Parra-Robles1, Jim M. Wild1

1Academic Radiology, University of Sheffield, Sheffield, South Yorkshire, United Kingdom

Dynamic radial 3He imaging allows rapid imaging of gas flow and can give information about lung motion and gas trapping. 129Xe and 3He dynamic radial imaging of an inhalation and exhalation manoeuvre were compared in a healthy volunteer. Comparable lung movement and gas filling was seen, despite the lower signal to noise ratio of the 129Xe images. Region of interest signal time-courses showed a faster rate of signal increase during inhalation for 3He than 129Xe, which may be due to the greater density of 129Xe. The rate of signal decay during exhalation was similar for both gases.