Meeting Banner
Abstract #4003

Quantitative Assessment of Compressed-Sensing Reconstruction Fidelity for 3D He-3 and H-1 Acquisitions in One Breath-Hold

Kun Qing1, Talissa A. Altes2, Nicholas J. Tustison2, Jaime F. Mata2, G. Wilson Miller2, Eduard E. de Lange2, William A. Tobias3, Gordon D. Cates3, James R. Brookeman<s

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States; 3Physics, University of Virginia, Charlottesville, VA, United States

The purpose of this work was to directly and quantitatively evaluate the reconstruction fidelity of undersampled compressed-sensing (CS) reconstructed 3D image sets by acquiring both the fully-sampled and undersampled acquisitions for a given nucleus (He-3 or H-1) in the same breath hold. Undersampled, CS-reconstructed H-1 3D images showed high similarity to their fully-sampled counterparts. While somewhat lower similarity indices were found for undersampled, CS-reconstructed He-3 3D image sets, this can be attributed to factors unrelated to the actual performance of the undersampled acquisition with CS reconstruction, including diaphragm movement, the non-equilibrium hyperpolarized magnetization, and B1 inhomogeneity.