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Abstract #4128

Proton MR Spectroscopy of Ovarian Tumors at 3T: Differentiation of Benign and Malignant Solid Components of Ovarian Tumors

Mayumi Takeuchi1, Kenji Matsuzaki1, Masafumi Harada1

1Department of Radiology, University of Tokushima, Tokushima, Japan

We evaluated ovarian solid, or complex solid and cystic masses by MRS at 3T. The choline concentration in 21 malignant tumors with predominantly solid nature (9.47 +/- 4.66 mM) was significantly higher than that in 11 benign lesions (5.48+/-4.77 mM) (p<0.05). Using a cut off value of 6 mM for malignant lesions had a sensitivity of 81%, specificity of 73%, PPV of 85%, and NPV of 67%. MRS can provide helpful information in distinguishing benign and malignant ovarian tumors, however, malignant tumors showing solid and cystic nature or containing necrotic areas tended to show lower choline concentration.