Clinical Significance of Lipid Peak in In-Vivo 1H-MR Spectroscopy of Uterine Sarcomas at 3T

Mayumi Takeuchi¹, Kenji Matsuzaki¹, Masafumi Harada¹

We evaluated 14 uterine sarcomas and 24 benign myometrial lesions by 1H-MR spectroscopy at 3T. High lipid peaks were observed in 12 of 14 sarcomas, whereas in none of benign lesions except for one lipoleiomyoma. The choline peaks were observed in 12 of 14 sarcomas, whereas in all 24 benign lesions. However massive necrosis in sarcomas may decrease the choline peak, the presence of high lipid peak may suggest their malignant nature. We conclude that high lipid peak in uterine mass without fatty component is suggestive for sarcoma, whether the choline peak is present or not.