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Abstract #4197

k-T ISD Compressed Sensing Reconstruction for T1 Mapping: A Study in Rat Brains at 3T

Jing Yuan1, Dong Liang2, Feng Zhao1, Yujia Li1, Yi-Xiang J. Wang1, Leslie Ying3

1Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong; 2Paul C. Lauterbur Research Center for Biomedical Imaging,, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; 3Department of Electrical Engineering and Computer Science, University of Wisconsin,, Milwaukee, WI, United States

T1 relaxation has potentials for investigating low frequency motional physiological processes but suffers from long scan time, susceptibility to motion and high SAR. We present the use of k-t ISD, a recently proposed compressed-sensing method for T1 mapping. The T1 maps of rat brains derived with and without CS were compared. The results show that T1 map can be accurately estimated from the highly compressed data with the reduction factor up to 10 in brain ROIs and 6 in muscle ROIs without significant differences. This technique is promising for accurate T1 quantification with remarkably reduced scan time and SAR.