Abstract #4211

In Vivo Simultaneous Multiple 19F Marker Tracking Using an Improved 3D Golden Angle Sampling Scheme

Tobias Hahn¹, Sebastian Kozerke¹, Ruben Pellicer Guridi¹,², Werner Schwizer³, Michael Fried³, Peter Boesiger¹, Andreas Steingoetter¹

¹Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; ²Department of Biophysics and Bioengineering, University of Barcelona, Barcelona, Spain; ³Dep. of Internal Medicine, Division of Gastroenterology and Hepatology, Zurich, Switzerland

This study presents the simultaneous in vivo tracking of three identical fluorine labeled capsules using an improved 3D Golden Angle based sampling scheme. Liquid fluorine marker was Perfluoro-15-crown-5-ether and capsule filling was 65l each. in vivo SNR for different reconstruction window sizes is given. Furthermore, the effect of constrained reconstruction onto the tracking reliability is studied, by multiplication of reconstructed 3D images covering a large temporal range with dynamic 19F images. SNR comparable to other tracking methods is found and good tracking reliability from a temporal resolution of 220 ms.