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Abstract #4212

Comparison Between EPI and RS-EPI at High Acceleration Factors

Samantha J. Holdsworth1, Anh T. Van1, Stefan Skare2, Roland Bammer1

1'Center for Quantitative Neuroimaging, Department of Radiology, Stanford University, Palo Alto, CA, United States; 2Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden

Readout-Segmented EPI (RS-EPI) has been proposed in a number of studies as a variant of EPI to reduce distortion in diffusion-weighted (DW) neuroimaging. With the increasing number of coils coming available with advanced phased-array technology that increases the capacity of EPI to achieve higher acceleration factors, and with advanced distortion-correction methodology, we present preliminary data that shows that EPI may be more useful for acquisition of DWI images in clinically-acceptable scan times. Here we compare EPI and RS-EPI data acquired with the highest acceptable GRAPPA-acceleration factor that we have been using with our 32-channel coil.