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Abstract #4238

Positive Contrast Imaging of Microhemorrhages in Patients with Traumatic Brain Injury

Wei Liu1, 2, Qun Zhao3, Haiying Tang4, Binquan Wang1, 2, Ping-Hong Yeh1, 2, Dominic E. Nathan1, 2, John Graner1, Hai Pan, 2

1National Neuroimaging Consortium, National Intrepid Center of Excellence , Bethesda, MD, United States; 2Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, United States; 3Department of Physics and Astronomy, University of Georgia, Athens, GA, United States; 4Uniformed Services University of the Health Sciences, Bethesda, MD, United States; 5National Neuroimaging Consortium, National Intrepid Center of Excellence, Bethesda, MD, United States; 6Walter Reed National Military Medical Center, Bethesda, MD, United States

Two positive contrast techniques using phase gradient mapping (PGM) and susceptibility gradient mapping (SGM) were investigated as complementary approaches of susceptibility weighted imaging (SWI) for microhemorrhage detection in patients with combat related traumatic brain injury. The results demonstrated that PGM and SGM improved the CNR for the local regional of interest and might provide additional information for diagnosis.