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Abstract #4422

Accelerated In-Vivo Liver 31P MRSI Using GRAPPA

Anshuman Panda1, 2, Scott Jones1, 2, Rahul Srinivasa Raghavan1, Keith Heberlein3, Radhouene Neji3, Ulrike Dydak1, 2

1School of Health Sciences, Purdue University, West Lafayette, IN, United States; 2Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States; 3Siemens Healthcare, Erlangen, Germany

31P magnetic resonance spectroscopic imaging (MRSI) of the human liver is of clinical interest but requires long scan times. We investigated the feasibility of accelerating in-vivo 31P MRSI of the human liver using GRAPPA and a dual tuned 8-channel 31P/1H coil. Successful implementation of 31P GRAPPA MRSI on the scanner allowed for reduction of the scan time for 2D 31P MRSI data across a whole liver slice from 25.75 min to 15.17 min, while maintaining quantifiable spectral data quality and alias-free metabolite maps. It was concluded that acceleration of 31P in-vivo liver MRSI is feasible using GRAPPA reconstruction.