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Abstract #4425

Towards 13C NMR Spectroscopy of Human Muscle at 7T Using Broadband 1H Decoupling

Eulalia Sers Roig1, Lijing Xin1, 2, Arthur W. Magill1, 2, Rolf Gruetter1, 3

1Laboratory of Functional and Metabolic Imaging, cole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland; 2Department of Radiology, University of Lausanne, Lausanne, Switzerland; 3Department of Radiology, Universities of Lausanne and Geneva, Geneva, Switzerland

The main difficulty while implementing 13C MRS in human scanners at high field is the need for decoupling of the single-bond 13C-1H hetero-nuclear J coupling by respecting the IEC guidelines for SAR. In this study we present a successful implementation of in vivo 13C MRS applicability at a 7T human Siemens system within a clinical platform, including the detection of in vivo Glycogen together with an experimental evaluation of an existing decoupling technique Waltz16 by exploring its feasibility in humans at 7T and comparing to CW decoupling.