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Abstract #4462

Accelerated Multi Echo Based Echo-Planar J-Resolved Spectroscopic Imaging: Implementation and Quantitation of Cerebral Metabolites

Manoj Kumar Sarma1, Rajakumar Nagarajan1, Neil Wilson1, Jon Furuyama1, M. Albert Thomas1

1Radiological Sciences, UCLA School of Medicine, Los Angeles, CA, United States

Four dimensional (4D) multi-echo (ME) echo planar (EP) based J resolved spectroscopic imaging (ME-EP-JRESI) technique is more robust and enables simultaneous recording of two dimensional (2D) JPRESS spectra in multiple regions with better spectral and spatial resolution than the conventional magnetic resonance spectroscopic imaging (MRSI) approaches recording one dimensional (1D) MRS. These results demonstrate that ProFit processing of 2D JPRESS spectra extracted from the ME-EP-JRESI data provides additional metabolites with reduced CramrRao lower bound (CRLB) values (< 20%) in rhe healthy human brain.