David Ouellette1, Neil Wilson1, Brian Burns2, Jon Furuyama3, Gaurav Verma3, Chris Roberts4, Cathy Lee5, Preethi Srikanthan5, Theodore Hahn5, M. Albert Thoma
1Biomedical Physics IDP, UCLA, Los Angeles, CA, United States; 2Biomedical Engineering IDP, UCLA, Los Angeles, CA, United States; 3Radiological Sciences, UCLA, Los Angeles, CA, United States; 4School of Nursing, UCLA, Los Angeles, CA, United States; 5Medicine, UCLA, Los Angeles, CA, United States
EP-COSI is a 4D spectroscopic imaging technique, acquiring 2 spatial and 2 spectral dimensions. One of the drawbacks of EP-COSI is the long acquisition times. In this work, SENSE was applied to the EP-COSI sequence to cut the scan time by half. The calf muscles of one healthy and one diabetic volunteer were investigated with EP-COSI SENSE. The resulting 2D spectra were accurately localized and were of sufficient quality to observe the olefinic cross peaks in the diabetic calf and the creatine 3.9 doublet in the tibialis anterior.
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