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Abstract #0191

Quantification of Hepatic Blood Flow in Portal Hypertension Using 4D-Flow MRI: A Meal Challenge Study

Alejandro Roldn-Alzate1, Alex Frydrychowicz2, Oliver Wieben1, 3, Scott B. Reeder1, 3

1Radiology, University of Wisconsin, Madison, WI, United States; 2Radiology, Universittsklinikum Schleswig-Holstein, Lbeck, Germany; 3Medical Physics, University of Wisconsin, Madison, WI, United States

Portal hypertension is an end-stage complication of cirrhosis that leads to dramatic and complex alterations in the hemodynamics of the liver. Phase contrast 4D-flow MRI methods hold great promise to overcome the challenges associated with comprehensive non-invasive flow measurements in the abdomen. This study demonstrates the ability of radial 4D flow MRI to quantify changes in hepatic and mesenteric flow in patients with portal hypertension who are undergoing a meal challenge. Expect flow changes in portal venous, hepatic arterial and mesenteric vasculature were observed, including altered flow patterns, and flow in varices and the azygos vein.