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Abstract #0211

Dual-Echo Diffusion-Weighted EPI for Better Sensitivity to Acute Stroke

Samantha J. Holdsworth1, Stefan Skare2, Kristen Yeom1, Michael U. Antonucci1, Jalal B. Andre3, Jarrett Rosenberg1, Matus Straka1, Nancy J. Fischbein1, Greg Zaharchuk1, Roland Bammer1

1Department of Radiology, Stanford University, Palo Alto, CA, United States; 2Karolinska Institute, Clinical Neuroscience,, Stockholm, Sweden; 3Department of Radiology, University of Washington, Seattle, WA, United States

Here we investigate an alternative approach to diffusion-weighting imaging (DWI) with the use of a parallel-imaging enhanced dual-echo sequence. It was found that dual-echo DWI is a powerful method for evaluating diffusion-restricting lesions. The long echo time of Echo 2 gives rise to DW images that exhibit superior sensitivity to diffusion lesions than DW images acquired at a shorter echo time; Echo 1 provides high SNR ADC maps for specificity to acute stroke; and the information from both echoes is a potential source of complementary information for the assessment of blood and mineralization products.