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Abstract #0258

Three-Dimensional MOLLI for Myocardial T1 Mapping Using Respiratory Navigation and Inversion Time Gating

Tobias Voigt1, Tobias Schaeffter2, Rene M. Botnar2, Jouke Smink3, Markus Henningsson2

1Clinical Research Europe, Philips Research, London, United Kingdom; 2Division of Imaging Sciences, King's College London, London, United Kingdom; 3Philips Healthcare, Best, Netherlands

In this work, a free breathing three dimensional MOLLI implementation using respiratory navigation and novel inversion time gating is presented. Mapping of T1 has been applied in patients with diffuse fibrosis showing differences in quantitative values between disease and control groups. Probably the most widely used cardiac T1 mapping method is MOLLI. MOLLI is acquired in a breath hold which limits spatial resolution and restricts coverage to a single slice. Free breathing three dimensional T1 mapping of the whole ventricle as introduced in this work can be performed using respiratory navigation and inversion time gating, resulting in high-quality T1 maps.