Abstract #0259

Assessment of Myocardial Radiofrequency Ablation Lesions with 3D High Resolution Free-Breathing T2 Mapping

Daniel A. Herzka¹, Haiyan Ding²,³, Farhad Pashakhanloo³, Karl H. Schuleri⁴, Aravindan Kolandaivelu⁴, Elliot R. McVeigh³, Henry Halperin⁵, M. Muz Zviman⁴, Roy Beinart⁴

¹Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States; ²Biomedical Engineering, Tsinghua University, Beijing, China; ³Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States; ⁴Department of Medicine, Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, United States; ⁵Department of Medicine, Cardiology, Johns Hopkins University, Baltimore, MD, United States

Radiofrequency ablation (RFA) has become first-line therapy for many cardiac arrhythmias. Differentiating between viable myocardium and injured tissue (necrosis or edema) in both ventricles and atria following RFA can help in predicting the recurrence of arrhythmias. High-resolution MR imaging techniques such as late gadolinium enhancement (LGE) are well-established for the delineation of lesions. More recently, quantitative techniques such as T2 mapping have been demonstrated for the evaluation of acute injury. Here we present, high-resolution, 3 dimensional (3D) whole-heart free-breathing T2 mapping for the post-procedural detection of RF ablation lesions and correlate the results to high-resolution in vivo LGE and ex vivo images.