Daniel A. Herzka1, Haiyan Ding2, 3, Farhad Pashakhanloo3, Karl H. Schuleri4, Aravindan Kolandaivelu4, Elliot R. McVeigh3, Henry Halperin5, M. Muz Zviman4, Roy Beinart4
1Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States; 2Biomedical Engineering, Tsinghua University, Beijing, China; 3Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, United States; 4Department of Medicine, Cardiology, Johns Hopkins School of Medicine, Baltimore, MD, United States; 5Department of Medicine, Cardiology, Johns Hopkins University, Baltimore, MD, United States
Radiofrequency ablation (RFA) has become first-line therapy for many cardiac arrhythmias. Differentiating between viable myocardium and injured tissue (necrosis or edema) in both ventricles and atria following RFA can help in predicting the recurrence of arrhythmias. High-resolution MR imaging techniques such as late gadolinium enhancement (LGE) are well-established for the delineation of lesions. More recently, quantitative techniques such as T2 mapping have been demonstrated for the evaluation of acute injury. Here we present, high-resolution, 3 dimensional (3D) whole-heart free-breathing T2 mapping for the post-procedural detection of RF ablation lesions and correlate the results to high-resolution in vivo LGE and ex vivo images.