Abstract #0266

Exploring Cortical Cytoarchitecture in High Resolution R1 Maps

Jos P. Marques¹, Rolf Gruetter²,³

¹CIBM, University of Lausanne, Lausanne, Vaud, Switzerland; ²LIFMET - Laboratory for Functional and Metabolic Imaging, cole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland; ³Department of Radiology, University of Lausanne and Geneva, Lausanne, Switzerland

In this work we explore the cytoarchitectonic information present in high-resolution (0.65mm isotropic) R1 maps at 7Tesla. We observe that R1 values decay from white matter (WM) surface to the pial surface and that the average R1 maps show a consistent qualitative agreement with the known myelin distribution throughout the brain. We further explore the spatial patterns of the R1 variation from WM to the pial surface and observe that it is possible to differentiate Brodmann areas, such as V1, from the shape of the decay.